https://boards.hellobee.com/ Pregnancy, Baby and Parenting blog, by Hellobee en Wed, 08 Apr 2026 11:34:45 +0000 https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1590283 Thu, 24 Apr 2014 17:03:00 +0000 red_seattle 1590283@https://boards.hellobee.com/ <p>Holy cow that was a novel! Oops. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1590281 Thu, 24 Apr 2014 17:02:36 +0000 red_seattle 1590281@https://boards.hellobee.com/ <p>Just wanted to join in a little. I have a balanced translocation between 13/14. This puts us at a less than 30% chance of making a baby with a trisomy which is "incompatible with life"-- but as I age (I'm under 30 still), our chances of creating a fetus with the trisomy go way up. It's an exponential curve. We've felt comfortable rolling the dice in the past and conceived totally healthy DS the old fashioned way. We fully expected/expect to experience miscarriages though going forward. It's because of the increased risks of passing on the gene, that I feel that it's too risky and too emotionally difficult to try to conceive naturally after I'm 30. If we still want to grow our family after that point (and we definitely want more), we'll either adopt or go for PGD + IVF. Probably adoption though. A friend of mine went through PGD + IVF and has had 3 children that way. Watching her go through it-- while very successful, obviously-- kind of convinced me that I'd rather adopt. I think for us, we're happy that we got one healthy bio kid, we don't feel the need to have more bio kids so strongly that we want to go through what our friends did. We haven't shut the door on PGD + IVF, it's still on the table though-- so I do want to hear how things go with everyone!</p> <p>And-- if anyone plans to go through CVS, I'm happy to share my experience. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1590159 Thu, 24 Apr 2014 16:27:31 +0000 SweetiePie 1590159@https://boards.hellobee.com/ <p>@LindsayInNY: Yeah and I think some offices don't have a lot of experience with PGD/might not even do it. Don't know anything about yours though (obviously!) :-) </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1590124 Thu, 24 Apr 2014 16:14:41 +0000 LindsayInNY 1590124@https://boards.hellobee.com/ <p>@SweetiePie: Thanks! So far I like my RE office but it's been so basic and preliminary that who knows down the road... </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1589950 Thu, 24 Apr 2014 15:23:01 +0000 SweetiePie 1589950@https://boards.hellobee.com/ <p>@LindsayInNY: I hope it isn't necessary, but if you go the PGD route, since you're in the same city as me, I can give you my REs info. Since we did IVF w/PGD and we were extremely pleased with him. Not just the fact that it was a success, but the entire practice was great and we like him as a person. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1589516 Thu, 24 Apr 2014 13:30:52 +0000 Mrs.Someone 1589516@https://boards.hellobee.com/ <p>@LindsayInNY: I'm good at passing on optimism when I see people needing it :) </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1589490 Thu, 24 Apr 2014 13:24:18 +0000 LindsayInNY 1589490@https://boards.hellobee.com/ <p>@Mrs.Someone: I need to be optimistic like you ;) Turns out, DH wasn't tested after all so he goes in tomorrow morning for it. And we're going to proceed with Clomid/IUI until we have a reason to stop... </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics/page/2#post-1589484 Thu, 24 Apr 2014 13:23:01 +0000 Mrs.Someone 1589484@https://boards.hellobee.com/ <p>@LindsayInNY: Yep, those are pretty much the stats that I found, but nothing was specifically said about French Canadians. So I would trust what you found then. Still though, 1 in 27 is a 3.7% chance. Pretty low! When do you get his results? </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589448 Thu, 24 Apr 2014 13:16:39 +0000 spaniellove 1589448@https://boards.hellobee.com/ <p>@LindsayInNY: I didn't get a chance to see what it was but DH is a carrier for Canavan (he is Jewish). The testing is never going to be 100% conclusive for me because I'm Asian, so they had to just decide I most likely don't have it. Apparently it is possible to be a different ethnicity and have a totally different mutation, but it happens so rarely that they just don't bother running that test. (As in they don't test for the uncommon mutations) The RE gave us the chance to talk to a genetic counselor before our IVF cycle in case we wanted to do PGD, but we decided the chances were just so miniscule that it wasn't worth worrying about any more. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589443 Thu, 24 Apr 2014 13:16:05 +0000 LindsayInNY 1589443@https://boards.hellobee.com/ <p>@Mrs.Someone: Oh really? I found these odds online: "ANYONE can be a carrier. The carrier rate for the general population is 1/250. Some evidence suggests people of Irish / British Isle descent have an increased risk over the general population between 1/50 to 1/150. French Canadians, Louisiana Cajuns and Ashkenazi Jews are all considered high risk with a carrier rate of 1/27." DH is French Canadian, just don't know how much... </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589423 Thu, 24 Apr 2014 13:12:36 +0000 Mrs.Someone 1589423@https://boards.hellobee.com/ <p>@LindsayInNY: Honestly I don't think your RE will let you even try. Of course they can't stop you from trying naturally though. I just looked it up, of the general population his chance of being a carrier is 1 in 250. Its a bit higher for those of Irish descent too: 1 in 50. The odds are in your favor! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589392 Thu, 24 Apr 2014 13:06:40 +0000 LindsayInNY 1589392@https://boards.hellobee.com/ <p>@Mrs.Someone: I think it's the 1 in 4 odd that's are tough... Meaning, there's a 3 out of 4 chance that a LO would be completely fine. But if we take that chance and LO is that 1, then what... Those are options I'm hoping we don't have to ever discuss. I hope (as always) that I'm just preparing for the worst. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589321 Thu, 24 Apr 2014 12:52:48 +0000 Mrs.Someone 1589321@https://boards.hellobee.com/ <p>@LindsayInNY: I think in the off chance that he is, it would be a straight shot to IVF + PGD like you mentioned. The disease itself is very devastating so its not something to chance. I really don't think you have anything to worry about though, I've never known anyone affected by it (and many of my friends haven't even bothered getting tested). </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589306 Thu, 24 Apr 2014 12:48:53 +0000 LindsayInNY 1589306@https://boards.hellobee.com/ <p>@Mrs.Someone: I deleted the actual term but don't mind discussing things otherwise :) I don't want to jump to conclusions but, yet I am, and worry about what we'll do if DH is a carrier too... I hope it's not a path we have to go down though.</p> <p>@Shutterbug: I never would've even suggested they test it which is why it's so random! We're waiting for DH's results now to see if it's an issue. And proceeding with medicated IUI this cycle too. I didn't really think about what genetic testing would entail because, in a way, you're kinda playing God. I'm glad it's something science has developed though, in an interesting way. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589294 Thu, 24 Apr 2014 12:45:13 +0000 Shutterbug 1589294@https://boards.hellobee.com/ <p>@LindsayInNY: my DH was tested for that as well because of his French Canadian lineage (he's not a carrier). They didn't test me because I didn't have one of the typical ancestries for it. It's good that they tested you regardless! </p> <p>Someone in my DH's family has SMA (spinal muscular atrophy) and when we first started TTC DH asked is PCP to test him for it. They had no clue what he was talking about, and they ended up doing the wrong test! Turns out he's not a carrier (though his sister is). When we started IVF they tested us both for SMA as part of their standard procedure. I'm all for genetic testing... the more you know, the better! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589290 Thu, 24 Apr 2014 12:44:20 +0000 Mrs.Someone 1589290@https://boards.hellobee.com/ <p>@LindsayInNY: Based on your description, thats what I thought. Its nothing to be ashamed of! Given your backgrounds its highly unlikely that will be a problem for you, but its much better to know now. </p> <p>As for where it came from, tons of people have unknown pieces of Jewish ancestry. This doesn't mean you do, but given that we have a very persecuted history, lots of people converted for safety reasons over the decades, especially around WWII. (let me know if you want me to delete this for your privacy) </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589250 Thu, 24 Apr 2014 12:37:51 +0000 Torchwood 1589250@https://boards.hellobee.com/ <p>@LindsayInNY: Thanks. Appointment is May 2nd, so I'll probably report back then. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589226 Thu, 24 Apr 2014 12:32:37 +0000 LindsayInNY 1589226@https://boards.hellobee.com/ <p>@Mrs.Someone: I might end up deleting this later but I'm a carrier for ((deleted)). The 1 out of 190 things that came back from my testing. And I'm as Roman Catholic as they come (all of my family too). I'm also from various European backgrounds so maybe that's it? DH is almost half French Canadian which is another likely carrier so I'm really hoping he isn't...</p> <p>@Torchwood: I saw part of your story when I was on vacation but didn't get to read it in its entirety... I hope everything is okay for you and LO though. &lt;3 </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589201 Thu, 24 Apr 2014 12:27:11 +0000 Torchwood 1589201@https://boards.hellobee.com/ <p>@LindsayInNY: Thanks for bumping this! We may wind up having to go this route, so it was good to read. And I hope things turn out better for you! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589133 Thu, 24 Apr 2014 12:10:12 +0000 Mrs.Someone 1589133@https://boards.hellobee.com/ <p>@LindsayInNY: Curious what condition you're talking about? Feel free to ignore the question if you don't want to share! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1589116 Thu, 24 Apr 2014 12:05:07 +0000 LindsayInNY 1589116@https://boards.hellobee.com/ <p>I did have the standard testing done - checked 190 diseases, I'm a carrier of 1. Something completely unexpected (as in, it's typical of a population that I'm not part of). If DH is NOT a carrier then we have a &lt;1% chance of a LO having it. If he IS a carrier, it's a 25% chance that a LO will have it. Which, from what I understand, means either IVF with PGD or testing once I'm already pregnant and discussing options if LO has it (terminate or not since it causes death usually before age 4 or 5). I really hope this isn't an issue that we have to consider... </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1588444 Thu, 24 Apr 2014 09:32:27 +0000 SweetiePie 1588444@https://boards.hellobee.com/ <p>@LindsayInNY: @Mrs.Someone: @spaniellove: Yes that's what I was trying to get at. We went straight to actual karyotyping because after my 2nd miscarriage the fetal tissue came back with a somewhat rare abnormality (partial trisomy 18...it's the partial part that threw a red flag).<br /> So, we got karyotyping done and sure enough I have a balanced translocation between chromosomes 18 and 20. Basically a part of those two are switched with each other. Since it's balanced in me it doesn't present any issues. But when our eggs are formed they only take on half of our chromosomes (I'm obviously majorly simplifying here, I'm not a doc!) so there's some chance (not sure how they calculate) that the "bad" chromosomes get passed on. For me, the chance is greater for bad than good. Basically 80-90%. Again, not sure how they calculated but that's what they gave me. And Trisomy 18 and 20 are very serious, usually fatal or severe disability. Most don't make it to birth and the ones that do usually only live a few days unless on major life support.<br /> So our best recourse was IVF with PGD. We started the process in September, started stims around thanksgiving, retreival early December. 13 retrieved, 10 fertilized, 8 survived the biopsy for PGD on day 5 and were frozen. Of the 8 biopsied, only 1 was normal. Remember that even without my own issues, every woman is going to produce some bad eggs "de novo".<br /> So on Jan 8th we transferred our 1 good embryo and now I'm 18 weeks tomorrow :-) He's healthy so far, all tests have been passed (NT, Verifi, sequentials, etc) and already moving around a lot so that I can feel him. </p> <p>Anyway, that's my story. I should save this so that next time I post about it i can copy and paste. Haha. </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1588265 Thu, 24 Apr 2014 08:57:22 +0000 spaniellove 1588265@https://boards.hellobee.com/ <p>@Mrs.Someone: @LindsayInNY: Agree, if it was "standard", it was most likely carrier testing (Counsyl is one example) and not karyotyping which is super expensive and rarer (often your insurance will want to know that you've had repeat miscarriages to cover it). Good luck with your results phone call! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1588185 Thu, 24 Apr 2014 08:38:11 +0000 Mrs.Someone 1588185@https://boards.hellobee.com/ <p>@SweetiePie: @LindsayInNY: Just to chime in, as far as fertility goes, I've heard of 2 types of genetic testing. The "standard" one is where you get checked for being a carrier of various things: CF, Tay Sachs, etc. </p> <p>Karyotyping is way less standard (I only had it done after 2 m/cs) and it checks that you have normal pairs of genes, ie. no translocations (genes stuck together). Just an example (not that this would ever happen), but if for some reason someone didn't know they had Downs, karyotyping would show that they had an extra copy of a gene. I didn't get any information about carrier status when doing it either, just that everything was fine.</p> <p>Hope all is well in your results @LindsayInNY! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1588132 Thu, 24 Apr 2014 08:22:27 +0000 LindsayInNY 1588132@https://boards.hellobee.com/ <p>@SweetiePie: I believe that's what it is? The RE made it seem like it was standard so we both had it done. I'm thinking something showed up in my results though... I don't know if I know yor story though? </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1587722 Wed, 23 Apr 2014 22:50:59 +0000 SweetiePie 1587722@https://boards.hellobee.com/ <p>We ended up having to do IVF w/PGD. Currently 17.5 weeks pregnant as a result!<br /> @LindsayInNY: When you say "genetic testing" are they karyotyping for chromosomal abnormalities?</p> <p> I feel like I have typed my story so many times everyone probably already knows it and is sick of it :-) But if there's anything specific you want to know, hit me up ;-) </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1587682 Wed, 23 Apr 2014 21:52:49 +0000 tequiero21 1587682@https://boards.hellobee.com/ <p>@LindsayInNY: good luck!! Hope all comes back with no issues! And that your first iui is a lucky one! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1587679 Wed, 23 Apr 2014 21:49:31 +0000 LindsayInNY 1587679@https://boards.hellobee.com/ <p>@tequiero21: Not yet. This cycle will be our first IUI though. My RE sent us both for genetic testing. I have a call for my results tomorrow so I don't know if that'll have any effect on things? </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1587677 Wed, 23 Apr 2014 21:47:29 +0000 tequiero21 1587677@https://boards.hellobee.com/ <p>@LindsayInNY: are u looking into ivf? If so, good luck!! </p> https://boards.hellobee.com/topic/experience-with-ivf-for-genetics#post-1586174 Wed, 23 Apr 2014 12:36:43 +0000 LindsayInNY 1586174@https://boards.hellobee.com/ <p>Bumping a really old post, hoping for some more responses/input!</p> <p>We're waiting for the results of our genetic testing still. Mine are back, but DH's aren't yet. We're trying to see up a call to discuss the results but I'm thinking about some things in the meantime. </p>