https://boards.hellobee.com/ Pregnancy, Baby and Parenting blog, by Hellobee en Fri, 17 Apr 2026 21:27:26 +0000 https://boards.hellobee.com/topic/mthfr-a1298c#post-936487 Tue, 16 Jul 2013 16:58:59 +0000 Mrs.Someone 936487@https://boards.hellobee.com/ <p>@Thenetexan: From what I've read, one copy of A1298C isn't much of a problem, so there might be something else causing your m/cs. My doctor is about to test me for autoimmune issues, though many people never find a cause. <a href="http://www.acfs2000.com/basic_services/repeated-pregnancy-loss-habitual-abortion.html">Here is a helpful link</a> that was shared with me on diagnosing and treating RPL. Hope you get some answers soon! </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-935987 Tue, 16 Jul 2013 14:04:51 +0000 Thenetexan 935987@https://boards.hellobee.com/ <p>Thanks all. I finally heard back from my doctor last night (the nurse posted the results online before he reviewed)... I have one copy of the A1298C. He said that this would not be cause for concern in pregnancy. If anyone else had a single copy and treated it, please let me know so I can push back. </p> <p>I had an uneventful first pregnancy that gave us our now very healthy toddler, but recently had two miscarriages in weeks 6 and 7. All the rest of my blood work was normal, so I guess we just keep trying. @Raintree: he tested multiple things, but I don't think homocysteine is one of them unless it has another name. I will certainly ask about that. Thank again. </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-931537 Mon, 15 Jul 2013 09:09:50 +0000 raintreebee 931537@https://boards.hellobee.com/ <p>@Thenetexan: I am compound heterozygous, like Mrs. Someone. During my pregnancy (I am 9.5 weeks), I was prescribed baby aspirin, a prenatal with quatrefolic acid (easier to absorb), and a supplement with extra folic acid and B vitamins.</p> <p>Were your homocysteine levels checked? Those give an indication of whether or not you are absorbing folic acid. Also, do you have one or two copies of A1298C? I have read that one copy of the A1298C is the least harmful of the mutations; next most harmful is two copies; next is one copy of each; and most harmful is two copies of C677T. </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-928363 Sat, 13 Jul 2013 02:57:48 +0000 blackbird 928363@https://boards.hellobee.com/ <p>I don't remember what mutation I have...I had two miscarriages (12 and 7 weeks), was diagnosed, and put on baby aspirin and folgard for my third. I carried to term and have a healthy 3 month old. Heart issues do run in my family, but I take WAY better care of myself. Mine hasn't caused any other issues for me </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-928288 Fri, 12 Jul 2013 22:40:43 +0000 Mrs.Someone 928288@https://boards.hellobee.com/ <p>@Thenetexan: I'm just now seeing this, and hopefully I can shed some light on it for you. </p> <p>I am compound heterozygous, meaning I have one of each of the mutations they test for. About 30% of Americans have one mutation, and I think around 10% has 2. What it means is that your ability to process folic acid is decreased. If you only have one mutation, its not that much of a problem. </p> <p>Unfortunately, it can cause miscarriages because blood is too clotty (I've had 2, though we're not sure MTHFR is to blame). It can also cause heart problems, and a bunch of other things.</p> <p><b>It is completely treatable, and you can have a healthy pregnancy and life with it. </b>Check out <a href="http://www.hellobee.com/2012/01/11/mthfr-c667t/">Mrs. Hide &amp; Seek's story</a>, she has 2 healthy kids.</p> <p>It is very important to be treated before pregnancy though, because a lack of folic acid can lead to neuro tube disorders (like spina bifida). There are also links to autism (something like 98% of autistic kids have at least one mutation)</p> <p>I am being treated with 5-MTHF, which is an active folic acid. Other people get treated with blood thinners, baby aspirin, or something like Folgard. Its quite a range based on what type of provider you see (I see a naturopath).</p> <p>Here are a few good resources for you:<br /> <a href="http://mthfr.net/" rel="nofollow">http://mthfr.net/</a> (includes list of recommended supplements, and problems caused by MTHFR)<br /> <a href="http://www.mthfrsupport.com/" rel="nofollow">http://www.mthfrsupport.com/</a></p> <p>If you haven't already, I'd highly recommend seeing a naturopath about it. They seem to be more knowledgeable about MTHFR. Good luck, and let me know if you have any other questions! </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-924239 Thu, 11 Jul 2013 18:41:28 +0000 SweetiePie 924239@https://boards.hellobee.com/ <p>Bumping for you! :) </p> https://boards.hellobee.com/topic/mthfr-a1298c#post-923500 Thu, 11 Jul 2013 15:35:43 +0000 Thenetexan 923500@https://boards.hellobee.com/ <p>This is not something I am familiar with and google has not been that helpful. What does a MTHFR diagnosis mean for future pregnancies and how is it treated? What does it mean for other health issues? I would love to hear your experiences; both positive and negative. Or if you have another good online resource to share, please do. Thanks. </p>