26 hour drive or 5 hour flight with a two week old?

We keep going back and forth on the pros and cons and while we still have six months before this is an issue, I was curious to hear other opinions. The main pro for flying is obviously the traveling time. The main pros for driving for us is not exposing our two week old to a plane full of germs and possible diseases, having a car on hand for the entire trip and not having to mail whatever gifts people will inevitably give us for the baby because we'll have plenty of room in the car, and just the fact that DH and I enjoy road trips.

I would love to hear thoughts on other pros and cons that we may not have considered yet. I also know this has been discussed previously on the boards but from my glance through, nothing was specifically for such a young newborn so I figured I'd bring it up