I usually avoid eye contact with them. Sometimes if I have a unopened soda or a snack that I'm not going to eat, I'll hand it over. I do have a soft spot for homeless women. If I have small bills on me and its easy to access, I might give them a bill or two. I do prefer giving them goods instead of cash so they don't spend it on drugs or alcohol.
Oh, I'm a softie around the hoildays, too.