I'm so upset right now. I was just away for a week and came back to my little cool select draw with a layer of frozen ice on the bottom. My 4 Gonal pens along with the Lupron were in the back left and the bottoms were soaked and caked with ice. I opened one up and it didn't seem to be frozen, I could still get the bubble to move in it. But is that too cold?? Did I ruin them??