Ovidrel is good until the expiration date refrigerated or at room temperature for thirty days. I do two ovidrel shots per cycle- one to trigger and a second five days later to improve progesterone. I had to have it shipped to DH's work and it arrived Wednesday and he put the entire box (ovidrel in styrofoam cooler) in the fridge. Winfertility says it is packed to keep cool for 48 hours. DH just brought it home last night (Monday). The ice packs were still cold by not frozen. The ovidrel boxes were a little cold but not very cold. I put them in the refrigerator immediately. Then due to RE scheduling, we will probably postpone their use til next cycle. It might not have been as cold for four days, but it will probably be about 35 days til I would use it. Is it still ok? I hate to waste the money.