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Can you do a four way alternation? I.e. Right buttock, right thigh, left thigh, left buttock. That's what we do for people who are having trouble with frequent injections, old people in particular. The two sites tend to absorb in a reasonably similar way. And it means a reduction of 50% in frequency per area.

Oh and it just sounds like you hit a vessel when you got bleeding. We aspirate a bit to check we don't get a blood vessel when giving IMs especially in the but. There is quite a small area that is suitable for injecting so don't stray too much in that area.

Yes, I definitely had this problem! I also developed a rash all over my bum which we tried to avoid while injecting too. Once I was sore all over and it was harder to find a spot, my husband (he always did the injections) would try to be more methodical about where he was injecting. So we'd sort of make our way through the target area (switching sides) in a pattern so we knew this was the area with the oldest injection sites (and hypothetically the most "healed") and here are the newer ones. But near the end of the 12 weeks everything was swollen, achy, bumpy, rashy, etc. and it was miserable. It will be worth it in the end!

@SweetiePie: it is a bit old school and I would think with everything that goes along with giving them to yourself it isn't really worth it. I like to do it in the but because you are more likely to hit a vessel. The worst that would happen is more bleeding, like you noticed, and in the worst case, a very painful lump, it just isn't something I want to inflict on my patients!
Also, do you count to ten before withdrawing? That gives time for the muscle to absorb the medicine and you are less likely to get stuff, including tha little drop of blood, coming back out afterwards.
Sometimes you do just get more blood than others and it isn't anything to worry about. If they let you do the thigh you'll have lots of place to inject and it'll give you time to heal.

@SweetiePie: I did the suppositories in addition to the injections too - yuck! I think I read somewhere that it takes 6 or 8 suppositories to equal one of the PIO injections. So you might have to increase your suppositories by a lot but it's worth asking if the PIO is just terrible for you! Either way I hope at your next appt they just say you're good to go and can be done with them!! It's so freeing when you FINALLY get to go off all the needles and shots and meds, etc.