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@spaniellove: So those are my 2 main issues. I have 2 MTHFR mutations (definitely find this out, many labs are connected to Microsoft Health Vault, which you can sign up for for free). I started on 1mg/day and upped it once a week until I was at 5mg. It is pricey, but necessary unfortunately Mthfr.net is a great resource too. For the autoimmune issue I take baby aspirin, and selenium for the Hashi's/thyroid. Let me know if you want my ND's contact info, she does phone consultations (though its out of pocket).

@Mrs. Jump Rope: Please find someone that is willing to do some testing. Preventing more losses is worth it! I had some testing after the first loss, and more after the 2nd (plus a long time to get the BFPs).

@Mrs. Jump Rope: I know its hard when everyone is telling you things should be fine. And the odds are very in your favor for having no problem the next time. But each loss is so heart breaking, some blood tests are worth it in my book. There is only a 4% chance of 2 in a row. I told my ND that I don't care what it costs, I wanted testing in hopes of preventing a third. This link was shared with me and it has helped a lot:
http://www.acfs2000.com/basic_services/repeated-pregnancy-loss-habitual-abortion.html

If I were you, I would either try and find a OB or ND that can help, or go a little farther away and look for a different RE. Otherwise, you can insist on them testing you. Tell them how hard the losses were for you, and that you're willing to pay for blood tests if insurance doesn't cover them (mine did, even though it sounded like they wouldn't).

I'm also on an "anti-inflammatory" diet, which means no gluten, plus some other stuff.

Edit: Sorry Spaniel, didn't mean to hijack the thread... I should've posted this to her wall.

I am diagnosed MTHFR heterozygous A mutation. So I only have one mutation. I also had the autoimmune testing done and was found to have issues there. Right now I am on Folgard (prescription folic acid), a prescription pre natal with tons of folic acid and baby aspirin daily. I had an egg retrieval last month for our first IVF and will do a FET next month. After the egg transfer, I will have to do daily Lovenox shots until at least 11 weeks of pregnancy. I have also done 2 intralipid transfusions so far and will need to do 2 more around the time of the transfer. The intralipids are for the immunology part of this. I will have the autoimmune blood tests done again after my last intralipid. One last thing, I am on an anti-inflammatory diet, similar to @Mrs.Someone, which is gluten and dairy free.

@spaniellove: I'm so sorry for your losses ((hugs))

Our insurance covers diagnostic testing for infertility. RPL is so new to me. I'm not sure if RPL testing is covered, and if it isn't, what the fees might be. My RE & OB are so positive that ill have a successful cycle next month that testing isn't on their radar -- and I've asked both parties more than once.

I had a lot of testing done before we started our journey at the REs office & they ruled our genetic testing, so I'm curious if I'm forgetting some blood test I had done that is making them so positive I don't need RPL testing.

Ill have to give them a call!

@spaniellove: my RE is in the Bay Area near San Francisco. He is known for the immune stuff. A lot of RE's don't believe in it, but this guy does. He has really good success rates, which I like. The only thing that i don't like is that the blood work for the autoimmune testing is not covered by insurance and it is expensive. I've had to do it 2x now. He does a baseline and then tests again after 2 of the intralipids. My numbers have gone down, just not enough so I need more intralipids.

@spaniellove: I'm pretty sure there are more bees with MTHFR mutations, but I'm blanking on who. Hoping they see this thread. I'm really hopeful that identifying this issue brings you much closer to a sticky baby!

@Mrs. Jump Rope: I also had testing after our second loss, even though the first one was so early. They ran a slew of blood tests, and I had an HSG. I agree, I would push for it, if you're comfortable. Most of the blood work took no time, and I actually got pregnant again on my HSG cycle.

Hugs to all. RPL is no joke. Sending love and positive vibes for sticky babies to everyone very soon!

@Mrs. Jump Rope: My first pregnancy was complication free and resulted a healthy, now 21 month old. I had two losses this year and my OB did initial progesterone check as soon as I got my BFP after the firs miscarriage and then did more blood work after the second. If he had not been willing to test, I would have gone elsewhere. Insurance covered it. In my mind, if there is any chance we can find out why and prevent this from happening again, that's what we should do. @spaniellove: my testing indicate the most common MTHFR which is a single mutation of the one that ends in 98c. My OB thinks that is not a problem... Not sure what I am going to do about that. I do already take a high dose of folic acid. I need to make my annual appointment and ask him to test for the folic acid absorption.

Bumping this up as I just found out I have a MTHFR mutation. my ob prescribed lovenox and referred me to a maternal fetal medicine specialist. Just looking for more info as she explained very little to me about what this means. I am 8 weeks and had 2 m/c in the past, which were at least in part due to a septate uterine wall which has since been removed.

@magnolia: if it's just one mutation that may not be a big deal.

@magnolia: I'm a bit surprised that you we're prescribed Lovenox for MTHFR. I was only put on it after finding several autoimmune issues (in addition to 2 MTHFR mutations). Hopefully your MFM will be able to provide more insite for you! Also, MTHFR.net is a great resource. In the meantime, make sure your prenatal includes Folate, not Folic Acid. Best wishes on your pregnancy!

@magnolia: I take the New Chapter Prenatal. There are very few that have just Folate, but its not as big of a deal if you just have the one mutation. I would think that you're on the Lovenox because of the other 2 conditions, you definitely shouldn't be on it just for 1 MTHFR mutation (something like 30% of the population has one). Its used for various clotting disorders, which hemochromotosis sounds like. I was put on it a few days after ovulation (I also had 2 m/cs), because I also had trouble concieving.

Your OB doesn't sound very helpful, especially since she didn't tell you about the injection! Do you see the MFM soon?

@Mrs.Someone: so sorry about your losses. Thank you so much for the info and reassurance.
I am going to try new chapter vitamin. I used it in one of my previous pregnancies, I don't love having to take it 3x a day but it sounds like its worth it.
The OB I usually see has been out on vacation almost since the beginning of my pregnancy, so I have been seeing another provider in his practice. I go back in less than two weeks so I guess I will take the lovenox until then. I am waiting for the MFM office to call me for my appointment.... Hopefully I get some answers soon! Thanks again.

@Mrs.Someone: ah! That's great to know. I just ordered some. Been trying to eat lots of dark leafy greens since the beginning of my pregnancy to get natural folate. Thanks again