I am using Endometrin suppositories (2 x day) during this IVF cycle, and used them last cycle as well. I also had a PIO shot the day of my ER (Thursday) and I won't use the Endometrin tomorrow because I will have a PIO shot after my transfer.

I have been experiencing hot flashes today that have been pretty intense. I don't remember experiencing this during my first IVF cycle. Has anyone else had this side effect with Endometrin?

Also, did you all lay down for a half hour after using Endometrin? The manufacturer says you don't have to, but my nurse said to lie down. My nurse is notorious for giving inaccurate information, so I just wanted to see what everyone was doing.