I grew up in Virginia and it was pretty humid in the summers! Mostly though we just kept all the windows open, except on the worst days.
Went to school in the NE and didnt need it except for one summer I spent on campus. Lived in SF and didn't need it.
In NYC, I've mostly had window units. Our last apartment had central which was great, until it went out for several long months last summer. I learned that having no a/c is a much bigger deal when you have kids!
I'd say I had some form of a/c for 2/3 of my life. How much of your life have you had air conditioning?