Was surprised to read this - I had always thought that anti-depressants during pregnancy were considered relatively safe!

<< ResearchGate: What were your results?

Anick Bérard: Using antidepressants, especially selective serotonin reuptake inhibitors (SSRI), during the 2nd/3rd trimesters of pregnancy increases the risk of having a child with autism (87 percent increased risk of autism with any antidepressants; more than doubling the risk with SSRI use specifically) – this risk is above and beyond the risk associated with maternal depression alone (maternal depression was associated with a 20 percent increased risk of autism in our study). Given the mounting evidence showing increased risk of adverse pregnancy outcome with antidepressant use during pregnancy, our study shows that depression should be treated with other options (other than antidepressants) during this critical period.

Indeed, 80-85 percent of depressed pregnant women are mildly to moderately depressed; exercise and psychotherapy have been shown to be efficacious to treat depression in this sub-group. Therefore, we acknowledge that depression is a serious condition but that antidepressants are not always the best solution.

RG: We normally think of the first trimester as being the riskiest time for the fetus, but this study was actually in the second and third trimesters. Why is the risk greater later in pregnancy?

AB: 1st trimester exposure is problematic for embryogenesis; 2nd/3rd trimesters are critical for brain development. Hence, the critical time-window for our study was the later part of the pregnancy. >>

https://www.researchgate.net/blog/post/antidepressants-taken-during-pregnancy-increase-risk-of-autism-by-87-percent

The Times added some much needed context to that 87% increase:

<< That headline-provoking number represents a relatively large associated increase in what begins as a small number: Among the pregnancies studied, the rate of diagnosis of autism rose from less than 1 percent to less than 2 percent of children when the mothers were taking antidepressants. >>

http://parenting.blogs.nytimes.com/2015/12/14/new-research-raises-more-questions-about-antidepressant-use-during-pregnancy/