What time frame would you prefer if they were going to come for two weeks? This is assuming that you'll be getting complete help from them (i.e., they'll be doing the cooking, cleaning, etc.) and LO #1 will be in daycare. Will your answer change if you end up having a c-section?
I realize this doesn't really apply to those who have family nearby. This is really a question for those who don't have family close by.
I originally thought i'd want them to come when i have the baby, but we have some options for when i go into labour. I found the first two weeks relatively easy (minus the trip to the hospital because of her jaundice) and the worst was from week 3 to 6!