. I talked to my mom and she will do whatever I need, including shots, so I don't need to worry about that. I've given myself all the different injections in the abdomen, but for some reason, the PIO scares the crap out of me! 
!
even though I know you were hoping for more. And now you can heal and get your body in the perfect shape for those two in a little bit! 
This thread has been closed by the original poster.
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@GreenThumb: oh no! He says this with a smirk on his face?! what the heck is it with guys. I'm sorry..have you guys talked about it more and what you will do? I really wish you could do your FET as planned. Second thought - if it works out, is there any way for you to go with him to Switzerland and enjoy some 'relaxing' time there after your FET? When will he know which week it is?
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@GreenThumb: do you have a date scheduled yet? IF i don't need a second biopsy, we're looking at sometime the first couple weeks of April to do one last FET before switching to the new local RE for a fresh cycle sometime in the fall. And DH can only take off the afternoon after transfer and one day after, so I hear you on the needing a break while chasing a 3 yo!!! I can't ask my mom to come because she wasn't super excited about us doing this in the first place, so I don't think her being here would be good for this process
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@TeamJH: Thanks, maybe that's why I've been enjoying anything with soy sauce this week. I think I'll go pick up some pickles too!
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@GreenThumb: unless you are really scared of needles, PIO by yourself isn't too bad! I did all of mine myself. My left side was harder since I'm right handed but it was doable. Someone else had to do them alone, forgetting who...but I have a list of tips to make it easier. I'll have to search for it! You'll be ok!
Maybe ask your mom to come for the first one. I did find it easier if I did the sticking and my husband did the plunging but we only did that when we were both around (so maybe half of the time). -
@GreenThumb: the PIO shots really aren't bad to do by yourself. DH did the first few then had something he was going to be gone for. He offered to skip it but I didn't think that was necessary. I had him coach me the first one in front of a mirror. It actually hurts less when you do it yourself. The hardest part is knowing where to aim. I had bruises by this points I I knew roughly where to go but you could draw circles.
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@endymion4: @NorthStar: @SweetiePie: @AmeliaBedilia: @PurplePumps: Thanks ladies - I know it will be fine. I was just upset in the heat of the moment. DH is really so focused on his job right now (which I really do support) so it is hard for him to "remember" there are other things going on in his life
. I talked to my mom and she will do whatever I need, including shots, so I don't need to worry about that. I've given myself all the different injections in the abdomen, but for some reason, the PIO scares the crap out of me! We had our WTF appt. with the RE this morning. So FET will likely be scheduled mid-April. He really didn't have much to say about the failed cycle. Embryo looked great, my lining looked great, etc., so the take away was it was just bad luck (i.e. there was a genetic abnormality with the embryo). Which is only kind of comforting at this point. So he also said that their general cutoff for transferring 2 vs 1 is age 38 (when everything else looks good), which is why they recommended 1 for the fresh. I will be 38 in a month, so he said that it is up to us whether we do 1 or 2 for the FET. The 3 remaining embryos are all expanded blasts of good quality, so that's good.
@endymion4: He said that I could stop metformin (we used it during the fresh to moderate hormone levels so that I wouldn't have OHSS again, so he doesn't see a need for it with the frozen... interesting). I will take the Lovenox, although I'm not sure he totally agrees with my hematologist about the need for it. The only difference for me with this FET than the other 4 I've done before it that they do both PIO and suppositories for progesterone. I've always done PIO only.
So when AF starts next week we are off to the races once again.
@NorthStar: Oh yes, I really wish we could all go to Switzerland together (we've talked about it before). Maybe if it happens in May instead and we get a really good tax return!
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@GreenThumb: Thanks for sharing what your RE said! I think at this point before we move on to a whole new cycle, we're in the camp of using anything that may or may not help, but won't hurt
It's going to be a long wait for the biopsy results to come back. On the one hand I want it to be normal so we can move on to our next transfer and not have to do another biopsy and delay another month to see what that biopsy says. On the other hand, I want it to be abnormal and for that to be the thing we switch to have success!
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@GreenThumb: thanks for the update. That's good and bad. I wish there was more they could fix but it sounds like you're in good shape. As for progesterone, my RE originally recommended crinone BID. I asked if there was a cheaper alternative ($600), and he said I could do prometrium BID plus 0.5cc PIO. I don't know if FET will be different.
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@endymion4: I totally know what you mean... it's like of course it's good news to NOT have a problem, but then there's also nothing to fix! It was interesting about the metformin. Do you know why your RE recommends it for the FET? It definitely can't hurt!
@AmeliaBedilia: The progesterone thing is interesting. I think for the FETs you're whole natural hormone system is suppressed which is why he recommends doing both types of progesterone. I really don't mind the PIO (as long as DH does the injection
) but I'm not really looking forward to the mess of the suppositories! For all but one of my FETs we did 1cc PIO daily. But for my first FET (which ironically was the one successful one) I did 1cc PIO twice daily. So I kind of do feel good that we are maxing out the progesterone support again. It is something different, so at least there's something to hold onto other than luck. How are you doing? Is tomorrow the start of stims?
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I dunno how much more of this discomfort and pain I can take! I'm trying to decide now if I should opt to freeze and do a FET. Doctor didn't really want to do that unless absolutely necessary since, while freeze and thaw rates are high 95%... that's still a 1/20 chance it doesn't make it... and with my luck, I'd be that 5%.
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@GreenThumb: She actually didn't. she just agreed to it when I brought it up. My PCP actually suggested it because I've been pre diabetic on and off over the last couple years (runs on both sides of my family and I'm able to control it with diet, but oh, i LOVE sweets ;)). And then prednisone increases blood sugar, so she just wondered if it might impact my IVF. Hubby looked it up and found info both ways (+ for repeated failures and some that showed no impact), so we're just adding it in (again as a, may or may not help, but won't hurt ;))
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@PurplePumps: So sorry you are in discomfort and pain. Does your RE do the new or old method of freeze? That would help me make the decision. Oddly enough, my RE strongly recommended a freeze-all cycle and FET was what ended up working for me with what I considered to be two bad looking embryos.
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@PurplePumps: I am so sorry that you are going through this! Have you been watching for weight gain? Have you had any followup bloodwork to look at your liver enzymes, E2 and other counts (CBC)?
I can only tell you my experience. First fresh cycle, moderate OHSS - never hospitalized, but did go to the ER once, 1 great quality embryo transferred, cycle failed. FET 3 months later, 2 embryos, successful singleton pregnancy. Looking back, a freeze all was never offered to me as an option, but I wish it was. I feel like I wasted a really good embryo because my body was so out of whack.
I can imagine that freeze all cycles are scary, but the prep for the FETs is just so much gentler on the body, taking that out of the equation as a potential complication. Maybe some additional counsel from your RE would be helpful!
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@endymion4: Definitely sounds like a good idea!!
ETA: I have diabetes in my family - my dad is actually on the same dose of metformin as I was - so I felt like it really could be a good thing. The RE actually left it up to me whether I wanted to continue on it...
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@GreenThumb: My weight seems to be holding steady (at least by my crappy scale). It had been about 2lbs increase since ER, so he said I probably had about a liter of fluid. But oddly enough, this morning it was down 3 lbs, though my belly looks the same. That probably from my lack of eating since Sunday. No additional blood test done yet. Just from describing my symptoms, he didnt' sound too concerned yet. Maybe I'm just being a wuss with low pain tolerance....
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@PurplePumps: Well, this might be one of those times to just trust his experience and go for it! Hugs!
ETA: Go with your gut! And I really hope you feel better soon!!
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They use vitrification. I weighing the chances of failure for both cases. Fresh transfer with my body so out of whack... or survival of freeze/thaw. I feel like I trust the survival/thaw process more than my body right now....
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@PurplePumps: When do you have to decide and let the clinic know? I wish it was a clearer cut decision for you. The fact that they use vitrification is great (does anyone do the slow freeze anymore in the US?)!
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@PurplePumps: This is such a tough decision and just know that there's not a 100% way to be sure about how to proceed. Just go with what you and your doctor feel is best.
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@GreenThumb: I actually do think some places still use the slow freeze.
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@GreenThumb: They will take a look at the embryos again tomorrow morning, so the final decision can be made then.
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@agold: I wish that wasn't the case
!
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@PurplePumps: OK, so you have tonight to sleep on it. Are you going to have to head to the clinic anyhow, or will you be able to decide with the RE in the morning before you leave? I really hope you are feeling great in the morning and it will be easier to decide. Take especially good care of yourself tonight!!
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@PurplePumps: so tough. My leaning is that a freeze all is more likely to work. There is debate on fresh vs frozen even without OHSS, so I think that tips the scales in favor of a freeze all. We had a failed fresh with two good looking embryos, nothing to freeze. My progesterone was 2.7 on trigger day, and his cutoff is 3. I wish I could do fresh- I hate the extra wait and cost, but my RE thinks this is more likely to work. I'd consider making the RE decide.
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@PurplePumps: While I see lots of advice supporting switching to a FET, and while I haven't done one, I'll say that I had a pretty severe case of OHSS and we did a fresh transfer and it worked. Even with my symptoms lasting almost 2 weeks and going to hospital twice, all was still successful (though I didn't really get the majority of the symptoms till 5 days post transfer and got worse from there. Meaning there was no suggestion or reason to switch to FET).
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@GreenThumb: Yeah, I won't have to leave until just after the call if we decide to move forward with the fresh. I thought I was feeling great this morning, I was even able to sleep on my side for a little, but now at work I just feel like crap again. Maybe this just means I should just take some time off work and stay at home with my feet propped up lol
@AmeliaBedilia: I was thinking about that as well. Especially since my last 2 cycles, my luteal phase was cut short at 11 and 12 days, even with progesterone and that has never happened to be before. If there was one thing I could count on was a 14/15 day lp, which leads me to think Im just all sort of messed up after these meds. -
@waiting4you: That is promising to hear too. I'm just going to wait to see until tomorrow and *try* not to stress to much about it for the next 18 hours.
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@PurplePumps: I'm so sorry you are feeling bad. I can assure you that you are NOT a wuss. I also had mild-to-moderate OHSS and it totally sucked. I was forced to do a freeze-all because of my E2 and P levels. Did they check those? I would base my decision on that as well as how you feeling in general (aiming for "good" or "great"). The success rates go down with higher P and E2 so a little data could help ease your mind and/or help you make the decision.
I was totally bummed to do a freeze all and very worried nothing would survive the thaw (we only had 2). Our embryologist said 99% of them do survive these days, even though the consent forms I signed said that most do not! (And then I was verbally assured that the embryologist was correct!) In the end, I think all of the waiting did my body good and I'm nearing 9 weeks now. You know your body best!
ETA: My body was really stressed out with stimming ... I mean, like totally did not recover from OHSS for 6 weeks at least after retrieval ... That's why I say that I'm glad I was forced to wait, as it's what my body needed.
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So to further complicate things, my doctor is leaving the clinic (another is moving in) at the end of March, so we would go right into prepping for a FET and March transfer. I could skip a cycle, and I think he would oversee my care, but then it would be a different doctor and clinic doing it.
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@PurplePumps: oh my goodness, how stressful! like someone else said, have they tested your progesterone or estrogen at all to see how they are? I suppose that it is too late in the day to see if they can do that today? ugh - I'm sorry. I can see doing it either way - it would be nice to get it done, especially with your doctor leaving soon. But, i also hear about so many successes with FETs. I send strength in making your decision.
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@PurplePumps: I just wanted to circle back and wish you all the best for tomorrow. Whatever decision you and your RE make will be for the best!
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@Purplepumps: I was fortunate enough that work allowed me to take off an entire week to heal from the ER, can't imagine what you must be feeling while at work! My RE suggested a freeze-all cycle too as an option since I was bloated and uncomfortable since the ER. Luckily by transfer day I was still bloated but was able to move around, so we opted to do a fresh transfer and got the BFP. Good luck with your decision!
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And then there were 2. Just 2 blast left today. I'm thrilled to even have blast given the results before, but I was hoping for some miracle and more of them. We decided not to do the transfer today. As soon as I get my period, we'll move into prepping for the FET.
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@PurplePumps: two is good and having blasts is even better! I think that you made a great decision to let your body heal some. I know that it is a let down and sucks that you have to wait another month, but you are doing what is right for those snowflakes!
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@PurplePumps: I also think you made the right decision. Having two blasts is great! I'm really happy for you
even though I know you were hoping for more. And now you can heal and get your body in the perfect shape for those two in a little bit! -
@PurplePumps: Two is good! I only had one and he's now my 17 month old little meatball
I agree that it sounds like you're doing the right thing by freezing and waiting. The month will go by before you know it. Do you have anything fun planned to help the time pass? -
@PurplePumps: So amazing there are
two , though I totally understand the letdown. We had a bunch at retrieval....and then just some fertilized.... and then just two blasts to freeze. I was so upset to not have a few more, but nature has a way of doing the right thing even in these medicalized circumstances. I'm so excited you will have a chance to feel better and have the best conditions for your FET! -
@NorthStar: @GreenThumb: @SweetiePie: @Amorini: Thanks ladies. I'm just gonna be a nervous wreck now for another month until they thaw, and then another 2 weeks until results, and then I'm sure I'll find something else to stress over. lol. I do think this is the best choice. I'm still hurting and adding to the list of ailments crazy chest pains today.
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@PurplePumps: yea for two blasts! I hear you on wishing for more. It's so hard to know how many any of us actually need. Those could end up as two babies, which would be amazing! I think you made the right decision. I'm doing a freeze all this cycle and if all goes well, will do a FET in April, so maybe we'll be FET buddies.
AFM, we are cleared for takeoff. Cyst is shrinking, so I start stims tonight. My RE told me a recent study came out that made him think of me- they did a study on undetectable AMH- mine is 0.27, so not quite as bad. They looked at which factors indicated prognosis. He said I have all the favorable factors- age <38, good FSH (6), good AFC, normal BMI, so he wanted to give me some reassurance that he thinks we have a good chance. We also talked about the RI conversation and he was very open to all of it. I told him where we were on surrogate (that if we needed IVIG and it's not covered by insurance, the cost is about the same as a surrogate if we don't go through an agency, and the chances of success are higher). He is clear that we want a baby with DH's sperm and my eggs, but aren't significantly attached to me carrying it. He thinks I will be able to carry, but depending on labs and how things go, is willing to work with us either way.
Tonight:
follistim 300
menopur 150
HGH 2.9mg
DH and I both start a z-pack. I forgot to ask why he does this. Does anyone know? -
@AmeliaBedilia: Great news! So glad you are all set to go
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