Would you leave a job with great hours for a job with better pay?

I work in a specific area of healthcare and my goal has always been to eventually get a job at a hospital. I was planning on staying at my current job longer but we've had a change in management and things are going downhill fast. I have great hours (Monday -Friday 8-4). If I switch to hospital, the pay will be better but I may have to do overnights for a period of time or do rotating shifts. My kids are young (3 years and 8 months) so I'm unsure if I should jump ship now or wait.