How was your transition back to work & daycare after having LO2+? Any tips or special concerns for round 2?

I'm going back to work in two weeks after having LO2. He'll be 4 months and DD is 2.5. She's been going to day care while I've been on leave. The kids will be at the same one room, in-home day care that provides food. I'm thinking things won't be too complicated in our circumstances but I'm worried I'm missing something big.

My parents are coming for my first two weeks back to watch LO2. Then DH may watch LO2 for two more weeks. I wish we weren't doing that and that LO2 was going straight to day care so I (& LOs) could adjust to the new routine faster. DH really wants to LO to be a little older and save a month of daycare.