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I think you can do almost any vacation with an infant as long as you have realistic expectations on what you will be able to experience. I always like flying somewhere when they are infants since it is free and they are generally immobile. Plane trips get hard with toddlers. We have been to Los Angeles (Disney) and San Francisco when LO was under one. Staying with family, renting an apt or an efficiency type hotel is how we like to do it. It gets stressful in a small hotel room with a tiny fridge.

@gingerseaglass: we just went on a cruise with our 1 yr old nice and 4 yr old nephew and they were charged full fare. I was shocked! I assumed they would get discounted fare since they barely eat and can't do much!!

We just went to the beach with our 4 month old and it was great! It was nice to be somewhere fun and not feel like we *had* to do stuff. Plus, like @sloaneandpuffy: said, "vacation + baby = not much of a vacation." It's more about making memories and less about relaxing

I live just north on London and we've taken our daughter there a couple times. The first time was when she was 3 months old. Its a beautiful city. I LOVE it. Id recommend anyone visit if they can.

That being said, I just booked us flights home to St Louis, C as a lap infant (i reserved a bassinet on the intl flights, but its not a 100% guarantee). I had to search carefully for them. On domestic flights, lap infants are free. On intl flights, you will pay 10% of a ticket. Some airlines are MUCH more kid-friendly than others, so research carefully. Make sure you have decently long layovers and that the planes you are flying and long distance in have accommodations for infants, not all do.