My in-laws live about 4 hours away so we drive to visit them once every few months. We usually drive during her sleep times (Late Friday night and nap time on Sundays).
This trip for Easter will be one of the first times not during her usual sleeping timestimes since I am hopefully getting off early on Friday.
It should be an adventure! She's pretty easy going regardless, so I'm not super worried.
Have you taken a road trip with LO or do you regularly visit relatives that live far away? How does your LO do?