Any experience with this? I had Mirena before LO2 and didn't take this. Insertion was kind of a bad cramp/pinch for like a second then some light cramping/spotting for a couple of days. It was really no big deal. I go to a different doctor and she said she prescribes misoprostol to take four hours before any IUD insertion. I looked this up and it seems totally mixed on if it's necessary and any side effects either way. I'm thinking of not taking it since I've had two babies, my experience was fine last time, and I'm having my period so I thought that made it easier anyway? Any experiences/info is appreciated! I go tomorrow so I'll need to decide soon!