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So sorry you're still not feeling well! I never had that magical relief in the second trimester with either of my pregnancies. I remember feeling like would last forever.

With my second baby, I took Unisom/B6 to help all through my second trimester. I think I stopped at some point early in my third trimester, though I don't remember for sure. It wasn't a miracle fix, but I think (maybe?) it took an edge off sometimes. Or at least at night, it made me fall asleep more quickly - and sleep was about the only time I felt well!

When mine wouldn't subside and diclegis did nothing, I was finally diagnosed with nexium. Took it for the rest of my pregnancy and it was a game-changer!

I'd start diclegis or unisom/b6, I don't think it's dumb to start now. It's not like you're starting a new job and there's any investment here, you can just take it for a few days and not overthink it; if it helps you even a little you'll be able to function much better. I say this at almost 39 weeks--my nausea went away at 12 weeks and then came back around 34 weeks, and the pill combo for me isn't really working, I think because it's more of a physical "my stomach is between my boobs" combined with terrible acid reflux problem. I just encourage you to take it because I wish I could! ETA saw your post above--if the Tums don't work, don't be afraid to take pepcid ac, it's a lifesaver.

@pachamama: Yes, I think I just used a walmart brand unisom. I seem to remember there were two varieties (different active ingredients) and I got the wrong one first. I have no idea if it actually works this way or not, but I felt like I acclimated or became desensitized to the drowsiness after a while. I'd been worried about being able to function if I was too sleepy, but then I had to remember I wasn't exactly functioning well in the first place.

I'll also echo the advice on the acid reflux issues. I forgot I took zantac in conjunction with the unisom/b6!

I second @caitcat: on the unisom/b6 combo. One of my best friends had terrible nausea and that's what her OB recommended and it made a world of difference. Hopefully you get to feeling better soon.

I also had constant nausea, but it turned out to be GERD, so I was on Prilosec from 12 weeks on and it helped a ton too! I had to an advair inhaler and tesslon pearls to get rid of the nasty cough from the stomach acid getting my esophagus, but that was for only a week.

@pachamama: yep I am the same way. I guess I am overly cautious

@pachamama: My heartburn/GERD manifested much like @snarkybiochemist: described hers. I always felt like I was going to puke any minute, but never did. I had the horrid barking cough because of it, but cleared it up in a week and the Prilosec kept it in check along with the nausea.

My last pregnancy it went past 20 weeks, maybe like 22-24? I feel for you, it's so hard! It hadn't been that bad previously, so even though I knew it could last a long time I was taken a little by surprise.

I was on Prilosec throughout the 2nd and 3rd tri and had to be really careful about what I ate even on the meds but my nausea was definitely reflux related. And I had never experienced it before pregnancy.