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I did it because I am an Ashkenazi Jew and so there are specific things to test for. I was tested and then my dh was tested when it came back that I was a carrier.

We are going to TTC at the beginning of next year, so this summer I did a full panel because my mother is a carrier for Fragle X. We had already made the decision to do IVF with PGD if I was also a Fragile X carrier since we would have been at risk regardless of DH because of how that disease is transmitted.

Happily, I did not inherit her bad X, but we did discover I was a carrier for Neimann-Pick type A - and we immediately had DH tested for that. He is not a carrier, so we can go ahead and TTC the old fashioned way. If he had been a carrier, we would have moved immediately to IVF with PGD.

I am SO happy we did it. There is zero history of Neimann-Pick in our family, and actually, there is zero history of Fragile X - we just discovered my mother was a carrier while testing for another problem. The test (we used Counsyl) really gave us a lot of knowledge, and I like knowing exactly what is being carried in our family so I can give that information to our future children down the road.

After TTC for almost two years we had it done. We found out my DH has an issue with his chromosomes. If it wasn't for infertility we wouldn't have done it.

We did. Both my husband and I are Ashkenazi Jews, so we had to do it to test for Tay Sachs. I knew that his brother and dad were positive, so we did it first. Since we were doing it, we decided to test for it all just in case. I like to know the facts before I go into something...especially in this case. I don't want to have to make the decision to abort or not based on the results. I'd rather make the decision to conceive or not. I have no idea what we would've done if something scary came back positive. Thankfully, everything is okay!

Even though I have an increased likelihood of being a CF carrier due to a family member who had CF (she is deceased) we opted not to test as we would have not pursued IVF with PGD for that particular issue.

@Newbee: Our RE had us meet with a genetic counselor but after answering all of her questions she didn't think we needed to go any further - there were no flags

We are both planning on getting tested before TTC and are in the process of coordinating it with our doctors. I hadn't thought about it either until my gynecologist recommended it, but it turns out my ethnicity has a high carrier rate for CF. My insurance won't cover genetic testing without medical necessity (and the ACOG guidelines aren't enough to justify it), but that ended up being a blessing in disguise because while trying to find financially reasonable alternatives I learned about Counsyl. It's a saliva test you can take at home that screens for ~100 diseases, not just CF. Most people can have the genotyping test done for $99 or less, which is worth it to us since we have no clue about any carrier genes in our families that we might need to worry about. Supposedly the more detailed sequencing test is capped at $199 (see http://boards.hellobee.com/topic/is-counsyl-still-99). I haven't verified this second figure with Counsyl directly, but the Director of Women's Health at Counsyl also commented on that post and didn't say it was wrong!

I know I sound like a commercial, but I swear I don't work for them! I'm just very excited about having found a more thorough and less expensive option