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@CupQuakeWalk: take them both in the morning on an empty tummy with a big glass of water, wait at least 30mins, or preferably an hour before any food or vitamins. Don't take it with juice or milk because it will effect the absorption. I take 50mgs each morning

I was on 88 mcg for almost 10 years (was severely hyperthyroid and had my thyroid ablated so became hypothyroid). This year my levels went up for the first time in forever and I just felt off (super cold and tired and shaky) and my levels were at a 4.7 which is the outer limit. My doc wanted to get me more mid-level - like closer to a 2 which is where I had been for a long time. She upped my dosage maybe 2 months ago to 100 mcg and my levels are already back around 2 and I feel so much better

I take one tablet first thing in the morning with water on an empty stomach. Then I go get LO and get her dressed and ready and make us breakfast and by then it's been more than 30 minutes since I took the pill.

Do you have 2 pills bc the dosage doesn't come at 50 mcg? I remember having that issue a long time ago. My instinct is it's ok to take both at once

@CupQuakeWalk: I would say to take them both together in the morning but I'm pretty sure they come in a 50mcg dose. I would clarify with your doctor.

I take 100 every weekday and 50 (half the pill) on the weekends. This has kept my levels around 2ish for a long time (down from 67 when I was diagnosed). During pregnancy I did have to up the dosage though.

I agree with the others... Never heard about taking them any other way than first thing in the morning.

I take .1mg in the morning. I can't do empty stomach so I do it about an hour after breakfast and at least four hours before my prenatal.

I (finally) got an awesome endo who said that the empty stomach thing isn't a biggie. The main thing is not to take the Synthroid/Levothyroxine with any other meds or vitamins, because calcium fights with the Synthroid. Worst-case, you may have to have an increased dose of the Levo, but for me, that's a small price to pay. There was NO WAY I could wait two hours after waking up before taking a pill! (The only time that worked was when I was pregnant and took it when I got up constantly to pee in the MOTN).
I take 200mcs 1x/day, but I take two pills, (400mcs) twice a week.
I hope you feel better!

I take one 25 mcg pill, but I'd think you'd take your full dosage all at the same time, even though it's 2 pills.

i take 50 mcg right when i wake up with a big glass of water, then wait at least 30 mins to eat. it used to be as 2 separate 25 mcg pills, until i started a new scrip and they gave me 1 50 mcg pill, so i think it's fine to take them together.